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This Advisory highlights the importance of methadone as a tool for treating incarcerated with people with opioid use disorder (OUD). The Advisory describes different institutional arrangements for providing methadone in correctional settings.

The Guidelines address the implementation of medications for opioid use disorder (MOUD) in state prisons and practical information about medications, service delivery models, regulatory requirements, staff training, and cultural issues that may affect the uptake and integration of MOUD.

This report presents data from DAWN using national estimates and trends of opioid-involved emergency department (ED) visits in the United States, including those involving prescription opioids, fentanyl, heroin, and opioids not otherwise specified.


Opioid misuse and use disorders among older adults are a growing public health problem that is often overlooked and undertreated. This increasing misuse and need for treatment can be attributed to several cultural, physiological, and systemic influences. This brochure discusses age-appropriate OUD prevention, treatment, and recovery approaches and provides key facts, considerations, program examples, and resources.

Medications for Opioid Use Disorder: An Effective Treatment for Justice-Involved Persons Reentering the Community Brief Reference Document explores how Opioid Use Disorder (OUD) treatment for justice-involved individuals will help lower the overdose risk for people reentering the community. It discusses treatment barriers, strategies to address them, and key reentry services to promote the successful reintegration of people returning to the community from incarceration.

Mobile Medication Units and Health Clinics Issue Brief demonstrates how these models can provide better access in communities where obstacles to receiving care exist and can support continuity of services, thus serving an important role in addressing the opioid crisis; highlights efforts in two states; and provides recommendations and lessons learned for offering mobile services.

Innovative and Holistic Programs that Offer Medications for Opioid Use Disorder to Pregnant and Parenting Women Issue Brief highlights two SAMHSA-funded grant programs—E-MOMS and KS HEART—to illustrate the implementation of critical service elements for women’s Substance Use Disorder/Opioid Use Disorder (SUD/OUD) treatment in two states.

This manual provides guidelines for operating an opioid treatment program. It covers patient-centered care planning, assessment, admission, and monitoring; medication administration and use; medical and clinical provisions and practices; certification and accreditation; and the importance of practitioner judgment in providing care.

This report looks at state and federal laws and policies that encourage braided funding to provide substance use disorder services, best practices for braiding funds, and pathways to sustainability for substance use disorder programs.
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